SpatialX EXPLORE: Multi-Modal Annotation for Cancer Pathology

Cancer is personal. Treatment should be too.

As co-founder and CTO of SpatialX (2024–2025), I architected EXPLORE — an AI platform that fuses spatial biology with digital pathology to make cancer treatment personal. I built it end-to-end, under HIPAA and ISO 15189, hands-on across frontend and backend.

I led the SpatialX patent from concept to delivery: an AI-powered Multi-Modal Annotation System, plus 5 research papers. The pipeline serves whole-slide images at up to 1M+ image-tiles per minute.

Tech: multimodal AI, spatial biology, whole-slide imaging (WSI), tile-streaming pipelines, AWS, Pulumi/IaC, CircleCI.

UX — An Annotation Tool That Feels Like ProCreate on iPad

Pathologists do not think in form fields and dropdowns — they think with their hands. So I built EXPLORE's annotation surface to feel like ProCreate on iPad: direct, low-latency brush strokes on gigapixel slides, pressure-aware marking, and pan/zoom that never fights the user.

The goal was zero friction between an expert's intent and the label that trains the model. Annotating a tumor region should feel like sketching, not data entry. The recording below shows the intuitive annotation tool in action on a whole-slide image.

SpatialX EXPLORE annotation tool — ProCreate-style direct manipulation on gigapixel whole-slide images.

SpatialX EXPLORE: Multi-Modal Annotation for Cancer Pathology | Mohammad Shaker